DNA repair mechanism through Protein NEIL3:
DNA, a nucleic acid which contain genetic information, used in the development and functioning of all known living organism and viruses. In this article we are going to discuss about NIEL3, a protein responsible for maintaining the integrity of DNA in Human and other mammals. Protein NIEL3 was first discovered in the year 2008 and since then it is considered as a basic DNA maintenance enzyme of type glycosylase.
It functions as a maintenance protein by patrolling the strands of DNA, checking for lesions-places where one among the four DNA bases has been damaged by radiations or chemical activity. While patrolling if it finds any damaged bases, it cuts those damaged bases free from the DNA backbone also kicking off follow-on mechanisms that links in the proper undamaged bases.
Looking at the importance of protein NEIL3 as maintenance protein, researchers and scientists took special interest in protein NEIL3 and came up with the common vicontinue reading